📄 Category

obstetrics and gynecology

49 papers

Obstetrics and gynecology encompasses the vital care of women's health throughout life, from reproductive wellness and pregnancy to menopause and beyond. This dynamic field explores the complex biological processes of childbirth, the prevention of diseases affecting female reproductive organs, and the latest advancements in maternal safety. It is a discipline deeply rooted in both immediate clinical impact and long-term public health strategies.

On Gist.Science, we continuously monitor medRxiv for the newest preprints in this category, ensuring you have instant access to cutting-edge research before formal publication. Our team processes every new submission to provide both detailed technical summaries and clear, plain-language explanations, making these complex studies understandable for everyone from specialists to curious readers.

Below are the latest papers in obstetrics and gynecology, offering fresh insights into the future of women's healthcare.

📄 obstetrics and gynecology

Efficacy and Safety of Oral L-Ergothioneine Supplementation in Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

In a randomized, double-blind, placebo-controlled trial involving 40 women, oral L-ergothioneine supplementation (120 mg/day) significantly and progressively reduced primary dysmenorrhea pain and associated symptoms over three menstrual cycles without adverse events, suggesting a cytoprotective mechanism independent of classical inflammatory pathways.

Guo, C., Liu, W., Ding, W., Cao, J., Tong, T., Liu, F., Xiao, G.2026-03-27
📄 obstetrics and gynecology

Hypoxia-associated gene signature for uterine cervical cancer

This study developed and validated a 55-gene hypoxia-associated signature that effectively stratifies uterine cervical cancer patients by identifying those with advanced disease features and significantly worse survival outcomes, suggesting its potential utility for guiding hypoxia-targeted therapies.

Datta, A., Biolatti, L. V., Reardon, M., Bigos, K., Lunj, S., Eke, H., Desai, S., Hyder, P., Reeves, K., Barraclough, L. (…)2026-03-25
📄 obstetrics and gynecology

Risk and timing of miscarriage and stillbirth in five low- and middle-income countries: evidence from longitudinal cohort studies

This longitudinal study of over 5,700 pregnant women across five low- and middle-income countries reveals that pregnancy loss remains a significant public health challenge with a cumulative risk of 103 per 1,000 pregnancies after 8 weeks, peaking in early gestation and among women over 35, while highlighting that conventional estimates often underestimate rates due to delayed enrollment.

Joffe, Z. T., Kone, S., Tesema, T., Mugenya, I., Mohan, S., Kruk, M. E., Arsenault, C., Fink, G., Clarke-Deelder, E.2026-03-25
📄 obstetrics and gynecology

Patterns and predictors of contraceptive use among post-caesarean women in Sierra Leone: insights from a five-year longitudinal study

This five-year longitudinal study in Sierra Leone reveals that while modern contraceptive use among post-caesarean women reaches 48.5% at five years, it is significantly influenced by increased health system contact, specifically higher antenatal care attendance and receiving contraceptive offers before discharge, whereas delivery at tertiary facilities is associated with lower uptake.

Banda, M. K., Twabi, H. H., van Duinen, A. J., Nliwasa, M., Kamara, M., Odland, M.2026-03-19
📄 obstetrics and gynecology

Association between Gestational Weight Gain on Obstetric-Perinatal Outcomes Among Women With Pre-pregnancy Overweight or Obesity in a Peruvian Public Hospital

In a retrospective cohort study of Peruvian women with pre-pregnancy overweight or obesity, excessive gestational weight gain was associated with a small but statistically significant increase in the risk of composite obstetric-perinatal outcomes, with the strength of this association varying by pre-pregnancy BMI class.

Hernandez-Concepcion, F. C., Pena-Cano, A., Davila-Quispealaya, J. E., Manrique-Franco, K., Yanac-Telleria, W. M., Yover (…)2026-03-14
📄 obstetrics and gynecology

Postpartum bleeding and shock in women giving birth with severe anaemia

Based on a cohort analysis of over 15,000 women in four countries, this study demonstrates that severe anaemia significantly increases the risk of postpartum shock independent of blood loss volume, highlighting the critical need for public health interventions to prevent and treat anaemia in women of reproductive age.

Mansukhani, R., Shakur-Still, H., Prowse, D., Geer, A., Brenner, A., Ker, K., Lieber, J., Balogun, E., Arribas, M., Chau (…)2026-03-13
📄 obstetrics and gynecology

Placental Pathways: The Impact of Air Pollution (PM2.5) Exposure on Pregnancy Outcomes in three Sub-Saharan African Countries

This prospective study across three sub-Saharan African countries provides exploratory evidence that higher personal exposure to PM2.5 air pollution is significantly associated with impaired fetal growth and lower birthweight centiles, though no direct links were found with pregnancy hypertension, preterm delivery, or stillbirth.

Makacha, L., Makanga, P. T., Tonne, C., Volvert, M.-L., Nunes, J., Jah, H., Sevene, E., Mukhanya, M., Koech, A., Wanje (…)2026-03-11
📄 obstetrics and gynecology

How just and fair are consent and debriefing for caesarean sections in Cameroon? An exploration of womens and providers perspectives

This study reveals that informed consent and post-operative debriefing for caesarean sections in West Cameroon are characterized by systemic injustices and unfairness, including informational deficits, cultural insensitivity, and the default absence of debriefing, which disproportionately disadvantage rural, low-income, and less educated women.

Tsuala Fouogue, J., Filippi, V., Tina Day, L., Matsui, M., Kenne, W. C. D., Kenfack, B., Benova, L., Sato, M.2026-03-10
📄 obstetrics and gynecology

Evaluating Mid-Upper Arm Circumference Cut-Offs as a Screening Tool for Undernutrition in Pregnant Women: An Alternative to Body Mass Index

This study validates mid-upper arm circumference (MUAC) as a simple and effective screening tool for identifying undernutrition in pregnant women in urban Bangladesh, suggesting a cut-off of <22.5 cm as a practical alternative to body mass index (BMI).

Sabed, S., Sharmin, I., Al Fidah, M. F., Khan, A.-R., Farzana, F. D., Mahfuz, M. T., Ara, G., Hossain, M. S., Ahmed, T. (…)2026-02-27